Synonyms :

Monocyte Chemotactic Protein-1, CCL2, MCAF, JE (murine)

Description :

The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant rat MCP-1 is a 14.0 kDa protein containing 125 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Catalog #:

400-12

Source :

E.coli

Purity :

Greater than 98% by SDS-PAGE gel and RP-HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Biological Activity :

Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml.

Selected References :

Selected List of References Citing This Product

AA Sequence :

QPDAVNAPLT CCYSFTGKMI PMSRLENYKR ITSSRCPKEA VVFVTKLKRE ICADPNKEWV QKYIRKLDQN QVRSETTVFY KIASTLRTSA PLNVNLTHKS EANASTLFST TTSSTSVEVT SMTEN

PubMed Link :

MCP-1+AND+rat

Country of Origin :

USA

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Usage: 
For Research Use Only. Not for use in diagnostic or therapeutic procedures.