Synonyms :

gamma-Interferon Inducible Protein 10, CXCL10, crg-2

Description :

IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells. Recombinant human IP-10 is an 8.5 kDa protein consisting of 77 amino acids including the four conserved cysteine residues present in CXC chemokines.

Catalog #:

300-12

Source :

E.coli

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Biological Activity :

Determined by its ability to chemoattract human T-Lymphocytes using a concentration of 10-50 ng/ml.

Selected References :

Selected List of References Citing This Product

AA Sequence :

VPLSRTVRCT CISISNQPVN PRSLEKLEII PASQFCPRVE IIATMKKKGE KRCLNPESKA IKNLLKAVSK EMSKRSP

PubMed Link :

IP-10+AND+human

Country of Origin :

USA

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Usage: 
For Research Use Only. Not for use in diagnostic or therapeutic procedures.