Synonyms :

Lymphocyte Activation Gene-1, CCL4L1, ACT-2, T-cell activiation-2, HC21

Description :

LAG-1 is CC chemokine that signals through the CCR5 receptor. LAG-1 is identical to MIP-1beta (ACT II isotype) except for two amino acid substitutions; arginine for histidine at position 22 and serine for glycine at position 47 of the mature protein. LAG-1 chemoattracts monocytes, and exhibits activity as an HIV suppressive factor. Recombinant human LAG-1 is a 7.7 kDa protein containing 69 amino acid residues.

Catalog #:

300-58

Source :

E.coli

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Biological Activity :

Determined by it's ability to chemoattract CCR5 transfected cells using a concentration of 0.1-10.0 ng/ml

AA Sequence :

APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRSKQV CADPSESWVQ EYVYDLELN

PubMed Link :

LAG-1+AND+chemokine+AND+human

Country of Origin :

USA

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Usage: 
For Research Use Only. Not for use in diagnostic or therapeutic procedures.